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The oxidative branch produces both ribose-5-phosphate (R5P), which is precursor for nucleotide synthesis, and NADPH, which is not only required for biosynthesis reactions but also for antioxidant response function

More recently, schisandra berry has been studied for its antioxidant, anti-inflammatory, and hepatoprotective properties

As a stimulator of ODC, Asn likely promotes TJs stability through increased polyamine synthesis, which is known to be essential for TJs protein synthesis and maintenance (Chen et al

It is thought that early induction of these antioxidative systems should significantly contribute to the protective mechanism of proline supplementation in this model