Clinical outcome was defined as death in 7 studies [12, 16, 26, 33, 34, 45, 54], intensive care unit (ICU) admission or requirement of mechanical ventilation in 6 studies [8, 10, 15, 17, 21, 23], prolonged viral shredding in 2 studies [43, 44], severe or critical (respiratory distress with respiratory rate 30/min, or oxygen saturation 93% at rest, or oxygenation index 300 mmHg, based on the diagnostic and treatment guideline for SARS-CoV-2 issued by Chinese National Health Committee [55] or the American Thoracic Society guidelines [56] for community acquired pneumonia) in 18 studies, the primary composite end point (ICU admission, the use of mechanical ventilation, or death) in 2 studies [18, 47], abnormal chest imaging in 1 study [52], acute cardiac injury in 1 study [19], progression of disease to more severe status (including increasing oxygen supplement, pneumonia exacerbation, transferred to ICU, and sepsis) in 10 studies [13, 20, 24, 25, 30, 32, 34, 37, 38, 48]
These drugs include the prescription and over-the-counter medications omeprazole (Prilosec), esomeprazole (Nexium), dexlansoprazole (Dexilant), and pantoprazole (Protonix)
Discussions with some of the respondents revealed that, among those who admitted to smoking occasionally but not being smokers, there were common criteria that many observed that technically kept them out of the smokers category
We hope to cooperate with the government to combat counterfeiting and smuggling of taxable goods, so as to avoid tax losses to the government
