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For the GSTO1 C4-10 complex, GSTO1 (2.66 mg ml 1 ) was incubated in a 1:1.5 molar ratio with C4-10 for 24 h at 4 C then concentrated to 26.2 mg ml 1

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Conversely, lipid peroxidation cascades, non-apoptotic cell death driven by iron-dependent phospholipid peroxidation involving arachidonate LOX-15 (15-lipoxygenase), glutathione peroxidase 4 (GPX4), polyunsaturated fatty acid-containing phospholipids, and Fe 2+ trigger itaconate production

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