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In subgroup analysis, the effect of drugs on overall success was assessed via a logistic regression model adjusted for polymorphism (bupropion-favorable polymorphism, varenicline-favorable polymorphism), sex, age, baseline carbon monoxide concentration, baseline heart rate, depression, anxiety, antidepressants/anxiolytics use, Fagerstrm test, Issa score, concomitant medications, chronic obstructive pulmonary disease, diabetes mellitus, systemic arterial hypertension, other diseases, and adverse events, taking the population on bupropion monotherapy as reference

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In the event said additional compensation is used to provide enhanced or innovative services at the Facility as compared to the services provided by the Department at comparable facilities, Contractor must still receive prior written consent from the State prior to receiving said compensation before the Contractor may retain those funds

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