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The brain substantia nigra in PD has a high level of expression of the VD metabolizing enzyme and 1 hydroxylase, and VD can stimulate the expression of tyrosine hydroxylase, a key enzyme of dopamine synthesis in PD, which affects the production and turnover of dopamine, therefore, the role of VD in the development process of PD has received increasing attention (85, 86)

Food Chemistry, 105(2), 727735

Protein (milk- or plant-based) and minerals (Zn/Se) are categorized as having moderate evidence, indicating potential but necessitating further targeted RCTfor instance, the efficacy of protein depends on bioavailability and an intake threshold of 1.2 g/kg body weight/day (252, 279) to avoid microbiota disruption

The plantar fascia supports the arch of the foot, provides shock absorption, and is important for proper mechanics during foot and ankle movement