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4 Discussion This systematic review and meta-analysis provide a comparative evaluation of oral, sublingual, and intramuscular (IM) vitamin B12 supplementation in the management of B12 deficiency

Our previous experiments have confirmed that the circadian rhythm disorder caused by changes in lighting interferes with the pulsatile release pattern of growth hormone in male mice and is accompanied by changes in the expression of peripheral clock genes in the liver (Wang et al., 2021)