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Redox-active small molecules (Methylene Blue): investigated for mitochondrial electron-transport-chain interaction and cellular oxidative-stress models

Briefly, Kokas extensor postural thrust (EPT) i.e., modified motor function index (MFI) assessed by an experienced, but naive, co-tester, as the weight on a digital weighing scale (precision 0.001 g) borne by the hind limb at the moment when the rat was held upright, with the hind limb extended and placed upon a scale, begins to bear weight on the scale, as follows: EPT = (NEPTEEPT)/NEPT (NEPT and EEPT represent EPT value before surgery (normal) and after surgery (experimental), respectively)

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