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Research suggests long-term use may help retrain the pituitary to produce more GH on its own

ClinicalTrials.gov, Identifier: NCT03057613 ( Post-operative Radiation With Cetuximab for Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck - Full Text View - ClinicalTrials.gov

Hilary Baldwin, medical director of the Acne Treatment and Research Center, has noted in published clinical commentary that "fish oil at standard doses is a reasonable adjunct when patients develop isotretinoin-induced dyslipidemia, provided they are monitored appropriately" [15]

541 Although these approaches facilitate drug design on a technical level, relying on a limited set of known SARs for pharmacophores may somewhat limit the structural diversity of the drugs and narrow the range of targets