J Nat Prod 63:10351042 Platzer M, Kiese S, Asam T, Schneider F, Tybussek T, Herfellner T, Schweiggert-Weisz U, Eisner P (2022) Quantitative structure-property relationship (QSPR) of plant phenolic compounds in rapeseed oil and comparison of antioxidant measurement methods
Most rodent studies used: 10 micrograms/kg 100 micrograms/kg Administration routes varied by study: Intraperitoneal injection Subcutaneous injection Oral administration in drinking water Example reference: Sikiric et al., 2018 These dosages reflect controlled laboratory conditions and are not generalised outside experimental models
ISOTINO 20 CAPSULE 10 is taken orally
Additionally, studies in mice have shown higher liver and kidney expression of Selenop in females than that in males (Schomburg et al., 2007), so SELENOP/LRP8-brain Se uptake pathway may also exert sex-dependence