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A practical rule of thumb: your largest planned weekly dose should require no more than 80 units (0.8mL) from the reconstituted solution

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10.1111/j.1751-7915.2007.00015.x Microb

Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, et al