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Nevertheless, the fact that the associations between alcohol and various cancer mortalities were non-significant using alternative lag structures raises some concerns about the robustness of these findings, and future work is necessary to develop the appropriate ways to estimate the complex lagged effects of alcohol and tobacco on cancer mortality outcomes

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D2-like receptors and G-protein coupling in the ventral striatum was also enhanced in combination with altered roles of D2 and D3 receptors in cocaine-induced behaviors