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Therefore, topical rapamycin should not be used by women who are pregnant, planning to become pregnant, or breastfeeding

2.5 In vivo therapeutic effects of Ru SA+AC on ACLT-induced rat OA model Given the remarkable enzyme-like properties, mitochondrial protection, and anti-inflammatory effects demonstrated by Ru SA+AC in vitro, its therapeutic potentials for OA were further investigated based on rat models of OA induced by ACLT, followed by intra-articular injection of g-C 3 N 4 and Ru SA+AC nanozymes

Taking into account the overwhelming body of evidence of novel functional role of RBCs in the cardiovascular system, it is tempting to put forward the hypothesis that anemia may not be a simple bystander in CVD, but may contribute to worsening the outcome