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This condition may arise due to insufficient dietary intake (resulting from several factors, including: a) the exclusive presence of B12 in animal-derived foods

Treatment with gonadotropin-releasing hormone (GnRH) analogues, estrogen supplements, oral contraceptives with low estrogen doses or progesterone alone achieves satisfactory prevention, suggesting the importance of maintaining adequate hypothalamic-pituitary axis regulation in CVS.58,59 The recognition of this subtype highlights the importance of a deeper understanding of the pathologic mechanisms of CVS, consequently providing highly efficacious personalized treatment

De complementariteit strekt zich ook uit tot de extracellulaire matrix (ECM)

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