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Daily consumption of B complex vitamins can lead to enhanced metabolic functions and support normal nervous system operations

Elevate homocysteine levels, impairing normal blood vessel function, promoting oxidative stress, and increasing risk of atherosclerosis, cardiovascular disease, insulin resistance, and Type 2 diabetes

In that study, a compensatory induction of keratinocyte lipid-binding protein was observed that was reported to overcome the functional effects of loss of adipocyte-specific aFABP/ALBP/aP2 (110)

Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential