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For the risk factor adjustment, the small numbers of missing values of cholesterol (40), BMI (1), percent predicted FEV1 (5) and father's social class (112) were imputed using the means for continuous variables or modes for categorical variables

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Common compliance elements include: Health warning labels, often covering a large percentage of the pack surface Plain packaging rules in some countries, limiting branding and imagery Mandatory legal text, including tax stamps or duty-paid markings where required Barcodes and traceability markings for supply chain tracking Age restriction notices, where legally required Country-specific labelling rules, which differ significantly by market Because these requirements change and vary by jurisdiction, always verify current regulations with the relevant local authority before producing or selling tobacco packaging

While Zyn is not FDA-approved for smoking cessation, it offers a less harmful alternative to tobacco