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Vitamin B12 is also available through a nasal spray (Nascobal), which is the way we most commonly prescribe it

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Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation

It has not progressed to extensive clinical trials, meaning its human safety and efficacy profile is not established it remains strictly a preclinical research compound