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4).8 Adolescent patients In the ALLEGRO-2b/3 trial, 15% of the population consisted of hard-to-treat adolescents with SALT 50% (severe AA), a mean disease duration of 6.5 years, and 40% with AT or AU.8 Although limited by small sample size, the results were consistent with those in the overall study population

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doi:10.4161/oxim.3.1.10476, PMID: 20716923 Morris G, Maes M (2013) Case definitions and diagnostic criteria for myalgic encephalomyelitis and chronic fatigue syndrome: from clinical-consensus to evidence-based case definitions