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Retrieved December 11, 2020, from HERE 5

A: Anecdotal reports vary, with some noticing changes in a week, while others may need several weeks depending on dosage and condition

Nature (2019) 573(7772):7582

Amphetamine undergoes further metabolic changes, resulting in the production of para-hydroxyamphetamine (pOH-AMP), 4 (phenylacetone), N-hydroxyamphetamine, and norephedrine (Figure 1).31 "Compound Summary"