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Figure 1 5.1 Omega-3 polyunsaturated fatty acids Omega-3 polyunsaturated fatty acids (PUFA) are a group of essential nutrients whose family members include alpha-linolenic acid (ALA), stearic acid (SDA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA) (111114)

Consequently, the use of the broad-spectrum GST inhibitor GSTO-IN-2 primarily reflects the effect of disrupting the broader GST-mediated antioxidant defense network, rather than selective inhibition of MGST3