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105 Intraoperative Doppler ultrasonography will greatly facilitate determination of the optimal degree of shunt attenuation in extrahepatic CPSS, helping to prevent severe portal hypertension.86, 87 Cellophane Banding Instead of a ligature, a 3-mmthin, three-layerthick cellophane band is placed around the shunting vessel with or without narrowing of the shunt diameter

However, the majority of GLS inhibitors exhibit poor solubility, inadequate selectivity, and limited bioavailability, among other inherent limitations

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