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Comparative data for both uncoated and coated NP are presented in Fig

Regarding gonococcal surface structures, including type IV pili and the CEACAM-binding protein Opa, these have evolved primarily to establish and maintain colonization while inhibiting gonococcal penetration, reducing their likelihood of encountering subepithelial immune cells, explaining why most female infections are localized and asymptomatic (Song et al., 2020)

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