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Comorbidities in chronic neuropathic pain

Fowler JS

Braak stage-related genes (BRGs) Two analysis methods were used to find BRGs for which the spatial expression in the AHBA is related to the progression of the disease: (i) Pearsons correlation between gene expression and labels 16 according to their assignment to one of the Braak stage-related regions R1R6, and (ii) differential expression between Braak stage-related regions R1 and R6

Major metabolites found were trimethylamine N-oxide, primarily in urine (8% to 49% of the administered dose) and [ 3H]--butyrobetaine, primarily in feces (0.44% to 45% of the administered dose)