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This process promotes the translocation of Nrf2 to the nucleus, triggering the activation of antioxidant response elements and increasing the expression of genes involved in antioxidant defences and anti-inflammatory responses [131]

Jurez E, Carranza C, Snchez G, Gonzlez M, Chvez J, Sarabia C, Torres M, Sada E

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There is a drawback however in using the weekly protocol, and this is attributed to an ineffective GHRH stimulation at around 1 am when GH should spike