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Methods Trial design and participants This phase 3, randomized, double-blind, placebo-controlled study was conducted at 41 sites across five countries (Canada, Italy, Hungary, Spain and the United States), as described in a previous publication 8 and listed in the Supplementary information

Vitamin B12 injections begin working almost immediately at a cellular level, though the timeframe for noticeable symptom improvement varies considerably between individuals

When administering vitamin supplements via injection, a much higher concentration of nutrients is delivered directly to the body's cells, allowing the body to better absorb and utilise these