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Michelle Oravitz: It's like I compare it to like, you know, the being able to take those pill things for your dogs where you put it inside a treat and get the dog to eat it

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The enrichment of genes associated with regional emphysema severity with COPD-related phenotypes in these other datasets suggests that the biological processes associated with increasing emphysema severity within a patient with severe COPD also vary in individuals with earlier stages of disease

Glucose and oxygen deficiency disrupts oxidative phosphorylation, which results in energy depletion and ionic imbalance, followed by cell membrane depolarization, calcium (Ca 2+ ) overload, and extracellular accumulation of excitatory amino acid glutamate