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For the other patients, titration started with a diurnal dose increase of approximately 20 mg every week (diurnal period from 57 a.m

This is probably mainly because of chelation between Cu 2+ and Qu since Cu-MSN also increased the loading of Qu (237.26 3.98 mg/g), while Zn-doping might not have significant contribution to the loading dose of Qu (82.30 2.05 mg/g) as compared to the MSN (Fig

In the NMDA-induced olfactory bulbs (OB) excitotoxicity model, the expression of SIRT1 and SIRT4 in OB increased, while the expression of SIRT2 did not increase, which may be related to the recovery of olfactory function [123]