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The intact hCG analysis revealed several hCG glycoforms

They concluded that while GHK-Cu does demonstrate anti-wrinkle effects in cellular studies, "there is a surprising absence of clinical studies using them." The review identified skin permeation as the central challenge: GHK's high aqueous solubility and low partition coefficient work against transdermal absorption

Electronic supplementary material 13058_2008_2172_MOESM1_ESM.ppt (download PPT Additional file 1: Powerpoint file showing the growth inhibitory effect of buthionine sulfoximine (BSO) and 17-estradiol (E 2 ) in MCF-7:2A cells is reversed by the antiestrogen 4-hydroxytamoxifen (4-OHT)

Neuroscience 129: 119127, 2004