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Nonetheless, the study recognized certain limitations, such as the focus on the occipital cortex rather than PD-relevant areas like the SN, small subgroup sizes that restricted disease-specific interpretations, and the absence of long-term follow-up studies

Yanaka argues that significant protection to the gastrointestinal tract is afforded by the modulation of oxidative stress and inflammation as a result of simultaneous activation of Nrf2 and downregulation of NF- B [216]

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Its safety profile is very good, with minimal side effects