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Because the oxidationreduction of Fe 2+ to Fe 3+ requires electron transfer, iron is involved in the electron migration between substrates ( 2+ or Fe 3+ ions and hydrogen peroxide (H 2 O 2 ) to produce highly reactive hydroxyl radicals (Lachaier et al., 2014)

Thus, GSH metabolism may play a critical role in hematological disease onset and progression

Swelling of the face, lips, or throat represents a severe allergic reaction requiring emergency treatment

Further information from the literature, CRISPR-Cas studies 32,33,34 , and the availability of suitable inhibitors were additionally used to identify candidate targets suitable for experimental testing