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MetS patients NO levels also increased with metformin ( In the Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication (DREAM) research, rosiglitazone reduced T2DM and improved normoglycemia in IFG patients

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SCALE found improvements in such cardiometabolic risk markers as lipid profile, blood pressure, and glycaemic control [82, 83], consolidated by pooled analysis in older and younger adults [84]