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In clinical trials for Barth syndrome, evidence suggests the drug is highly effective, yielding a 20-25% improvement in a six-minute walk test and a 40-50% improvement in leg extension strength

One patient developed low blood pressure and difficulty breathing and was transferred to hospital

Emotional and psychological stress are particularly common triggers that can intensify sweating episodes

Brain tissue homogenates and serum samples were collected to quantify intestinal permeability markers (zonulin and occluding), oxidative-stress markers (GSH, MDA, CAT), and GABA-receptor gene expression using ELISA and biochemical assays