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Here, a within-subjects comparison was performed using a two-way repeated measures ANOVA to assess mean differences in index scores between pre- and post-treatment conditions in the same animals

Side effects were rated using standardized tools such as the FISER/GRSEB/PRISE scales

Antiarrhythmic Medications Class I antiarrhythmic medications such as disopyramide and flecainide are sodium channel blockers that show an increased risk of heart failure