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In the coupling reaction, the iodinated tyrosine residues are combined by TPO to make triiodothyronine (T3) and tetraiodothyronine (T4), where MIT and DIT join to form T3, and two DIT molecules form T4

After incubation of the primary antibody at +4 for an hour, the cells were stained with a iFluor 488 conjugate-Goat anti-Mouse IgG Secondary antibody (HA1125) at 1/1,000 dilution for 30 minutes at +4

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Nevertheless, the pursuit of disease-modifying osteoarthritis drugs (DMOADs) represents another transformative direction ( FIGURE 5 Artificial intelligence (AI) and digital health technologies are increasingly being integrated into OA care