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Our finding is robust, because we demonstrated consistent results in a series of sensitivity analyses by excluding the subjects with ESRD occurring within 3 and 5 years of follow-up, and by adopting cause-specific hazard models, in which the death occurring before reaching the primary outcome was treated as a competing risk and censored

Evaluation of a murine liver colonization model revealed that PKLR promotes cell survival in the tumor core during conditions of high cell density and oxygen deprivation by increasing glutathione, the primary endogenous antioxidant

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In animal studies, the impact of DSIP has been shown to mitigate stress-related changes in GABA, glutamate, aspartate, and lipid peroxidation, highlighting its potential to alleviate anxiety (4)