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Standard doses: Low dose: 250mcg (0.25mg) Standard dose: 350-400mcg (0.35-0.4mg) High dose: 500mcg (0.5mg) A 5mg vial contains: 20 doses at 250mcg 14 doses at 350mcg 10 doses at 500mcg Why 5mg is the standard size Practical dosing : Matches typical 2-4 week cycles with twice-daily dosing

The overlapping receptor activation creates unpredictable effects and dramatically increases GI side effect risk

This cycling approach keeps intracellular NAD+ levels elevated without requiring continuous clinical visits

New models are in development: 1) Cell danger response 2) Horowitz 16 point differential diagnostic map 3) Dr Bredesen 36 point ReCODE program (Alzheimer's) 4) Biotoxin pathway from Dr Shoemaker There is no single treatment protocol though, no algorithm as each individual patient situation and chemistry is different