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Researchers called for urgent action to evaluate the potentially widespread exposure. In December, a San Diego Veterans Affairs lab investigation found that two e-cigarette products damaged cells in ways that could lead to cancer, even when nicotine-free

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According to research on tobacco composition, cured tobacco lines can contain between 0.2 and 4.75% nicotine by weight, depending on plant genetics, growing conditions, degree of ripening, fertilizer treatment, and position of the leaf on the stalk