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Through laboratoryexperimentationon various animals, including rodents, pigs, dogs, and humans, the unique mechanism of AOD-9604 has been identified, which primarily stimulates the release of fat from adipose tissue, inhibits the accumulation of new fat in adipocytes, and promotes fat oxidation

FIGURE 2 Uridine-induced change in body temperature is dose- and species-dependent

Oral intake of 2,400 mg/day for two weeks was also found to be safe in a pilot study that included participants with multiple sclerosis (95)

This cohort, known as the Taxonomy cohort 38 , comprised 156 stage II or stage III patients, 66 (35 male, 31 female) of whom went on to receive adjuvant 5FU-based chemotherapy (illustrated in Fig