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All participants will receive standard behavioral support and will be assigned to one of the following groups: Arm A: 12 weeks of placebo Arm B: 6 weeks of cytisinicline, followed by 6 weeks of placebo Arm C: 12 weeks of cytisinicline If participants qualify for and enroll in this study, they may receive the following: Cytisinicline (study drug), or placebo Study-related medical tests Financial stipend to help with travel costs and time All study medication and study-related care will be at no cost

Moreover, the high bioavailability of THC through vaping can encourage more intense use, potentially exacerbating dependence and neurocognitive risks

Unsurprisingly, several studies have reported that CBs are the most common item retrieved by clean-up activities in public areas such as beaches and parks [3,4]

The effects of e-cigarette minimum legal sale age laws on youth substance use