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Initially, the drug enters cells through the plasma membrane monoamine transporter (PMAT) and organic cation transporter 3 (OCT3) located on the surface of small intestinal epithelial cells

12,13 Other options include plasmapheresis, immunosuppressive agents (cyclosporin, cyclophosphamide, thalidomide), or various combinations of these options and any of the above treatments

Aging Cell 19, e13080

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