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Glutamine-derived aspartate induced by GOT2 is transported into the cytosol and converted by GOT1 to oxaloacetate, then converted by malate dehydrogenase (MDH1) into malate and subsequently oxidized into pyruvate by ME1 to create NADPH

doi: 10.1016/j.cmet.2014.05.004 67 AngiariSRuntschMCSuttonCEPalsson-McDermottEMKellyBRanaNet al

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