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A total extract from Cannabis sativa was used based on the fact that the effect of the whole plant which is abused by humans differs from that of THC in view of its content of other cannabinoids, terpenoids and flavonoids (Russo and McPartland, 2003)

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The activated Caspase-3 (Cleaved caspase-3) specifically cuts some proteins associated with cell activity and triggers apoptosis cascade reaction resulting in cell apoptosis [31]

Nielsen OH, Soendergaard C, Vikner ME, Weiss G