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[6] Assays for DBH activity in human serum and cerebrospinal fluid [edit] DBH activity in human serum could be estimated by a spectrophotometric method [12] or with the aid of ultra-high-performance liquid chromatography with photo diode array detector (UHPLC-PDA)

The simple and most accurate answer is: Yes, it absolutely can, but only if your fatigue is caused by a B12 deficiency

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While B12 injections for weight loss dont melt fat on their own, they can be incredibly useful for individuals who are low on energy and struggling with fatigue, two common hurdles on the road to weight loss