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There are many studies linking dietary supplements to telomere length, telomerase activity, and oxidative stress, and it was recognized that natural products with several antioxidants are more effective than taking one antioxidant, implying a synergistic effect between these compounds [289, 290]

HGF was first reported structurally similar to plasminogen in early 1980s, which was further characterized by a new substance responsible for liver regeneration in the serum of partially hepatectomized rats [3]

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