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Semaglutide is a glucagon-like peptide-1 (GLP-1) analog that was initially approved in 2020 as a treatment method for improving glycemic control in patients with Type 2 diabetes

The induction of genes encoding a sodium inducible calcium binding protein, a protein phosphatase, a PAL and GSTF7 were observed (Naidoo et al., Bacterial GSTs Bacterial genomes also harbor GST genes (Vuilleumier, GSTs of unknown function in bacterial and yeast genomes (Vuilleumier and Pagni, b)

In addition to disease states, extreme exercise causes nitro-oxidative stress and can disrupt resting glutathione levels