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Two-way within-subject ANOVA was performed, and the interaction of drug with time was analyzed by comparing data acquired after treatment for 1 month (visit 2), 2 months (visit 3), and 3 months (visit 4) relative to baseline (visit 1)

Individuals with obesity should be counselled to accumulate at least 150 minutes a week of moderate aerobic exercise, such as walking, and to engage in resistance training to preserve lean mass

In chondrocyte cultures, GHK-Cu increased the expression of type II collagen, the main structural protein of hyaline cartilage, as well as aggrecan, the most important proteoglycan for the compressive resistance of articular cartilage