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Pampelika extrakt Extrakt z pampeliky podporuje normln funkci moov soustavy a normln innost kardiovaskulrnho systmu, normalizuje hladinu cholesterolu a cukru v krvi

doi: 10.1155/2022/7888076 46 JangH

1c,ii), but because the sidechain of Tyr78 maintains a network of hydrogen bonds stabilizing the 1-1 loop interactions with helices 2 and 10, mutation to His78 will lead to a disruption of the hydrogen bond network, stability, and dynamics

The consideration of cysteine during these simulations were important, as cytosolic cysteine is the rate limiting amino acid precursor for synthesis of GSH, via the -glutamylcysteine synthetase (GCS) enzyme, and this is a function of its reduced concentration compared to the other precursors, glycine and glutamate