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It is essential for individuals to discuss their medical history with a healthcare provider before undergoing treatment to ensure that they are suitable candidates

A mean reduction of 20.4% at 68 weeks is clinically substantial, and the large, multinational phase 3 programme supports confidence in the efficacy estimate

There is no robust clinical evidence that B12 injections enhance energy, alertness, or performance in individuals whose B12 levels are already adequate

For example, a study using vegan donor FMT for cirrhosis patients found it induced significant changes in gut flora (such as Eubacterium siraeum and Blautia wexlerae ) and plasma metabolites (such as phenylacetylcarnitine) and affected hepatic DNA methylation profiles, suggesting FMT may act through multi-omics-level meta-organism pathways