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This is significant because, as further detailed below, the peripheral administration of APAP is linked to concentration-dependent in situ effects in the brain 17 , which could explain our observation of cognitive impairment and brain abnormalities with mild changes in the periphery even long after the final episode of hepatotoxicity

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Emerging research suggests that lower Glutathione levels may predict cognitive decline in healthy adults

I eventually discovered that my testosterone had dropped significantly and was the main culprit