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PLoS Comput Biol (2008) 4(1):e2.10.1371/journal.pcbi.0040002 51 SecciMEAuberAPanlilioLVRedhiGHThorndikeEBSchindlerCWet alAttenuating nicotine reinforcement and relapse by enhancing endogenous brain levels of kynurenic acid in rats and squirrel monkeys