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Laboratory research and clinical studies in dogs have investigated the potential role of supplemental PEA and other similar compounds in treating inflammatory skin, skeletal, gastrointestinal, and dental diseases

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A randomized multicenter trial

The amylin signaling pathway is distinct from and complementary to GLP-1 receptor signaling, as amylin primarily influences hedonic appetite pathways (reward-driven eating) while GLP-1 primarily affects homeostatic appetite regulation